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martin
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3/18/2022  10:41 AM
NYKBocker wrote:
smackeddog wrote:
martin wrote:
smackeddog wrote:Weirdly my sister's child got covid and she didn't (despite sleeping in the same room), and a few weeks later her partner has got covid and hasn't passed it on to her. How common is this? Have people encountered this? (either people they live with not passing it on or vice versa)? I've known a few people. Is it luck? Are some people more resistant to it? Is there much info about some people having an immunity to it?

I've known may families like this

I do wonder if it’s a fluke, or what the rates are of people with a robust natural immunity/resistance to the spiked protein, I’ve only read one or two articles and very small studies mentioning the research into it and even those weren’t really sure what’s going on.

At the beginning of the pandemic my wife got COVID. I was sleeping in the same bed for 2 nights. Until she finally got tested and tested positive. I took care of her giving her food and what not. I never got it. My family then went ahead and got the vaccine and boostered. Got a grandson and he is now 7 months olds. We babysit and I am with him almost everyday. My daughter and son-in-law got COVID at the beginning of the year and my grandson got it as well. They were both vaccinated. I still took care of my grandson. I just said...well I am getting it now. I am holding him and kissing him and everything. I never got COVID. So....

In my family, my wife, 2 daughters, son-in-law and grandson got COVID. Myself, 2 sons and daughter-in-law never got COVID. It is weird.

EDIT: I have been tested multiple times. I play basketball unmasked. I go to the gym unmasked after the NY mask mandate was lifted.

Obviously you are super human and we should all be drinking your blood

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NYKBocker
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3/18/2022  11:47 AM
martin wrote:
NYKBocker wrote:
smackeddog wrote:
martin wrote:
smackeddog wrote:Weirdly my sister's child got covid and she didn't (despite sleeping in the same room), and a few weeks later her partner has got covid and hasn't passed it on to her. How common is this? Have people encountered this? (either people they live with not passing it on or vice versa)? I've known a few people. Is it luck? Are some people more resistant to it? Is there much info about some people having an immunity to it?

I've known may families like this

I do wonder if it’s a fluke, or what the rates are of people with a robust natural immunity/resistance to the spiked protein, I’ve only read one or two articles and very small studies mentioning the research into it and even those weren’t really sure what’s going on.

At the beginning of the pandemic my wife got COVID. I was sleeping in the same bed for 2 nights. Until she finally got tested and tested positive. I took care of her giving her food and what not. I never got it. My family then went ahead and got the vaccine and boostered. Got a grandson and he is now 7 months olds. We babysit and I am with him almost everyday. My daughter and son-in-law got COVID at the beginning of the year and my grandson got it as well. They were both vaccinated. I still took care of my grandson. I just said...well I am getting it now. I am holding him and kissing him and everything. I never got COVID. So....

In my family, my wife, 2 daughters, son-in-law and grandson got COVID. Myself, 2 sons and daughter-in-law never got COVID. It is weird.

EDIT: I have been tested multiple times. I play basketball unmasked. I go to the gym unmasked after the NY mask mandate was lifted.

Obviously you are super human and we should all be drinking your blood

One word of advice for you.... commando

martin
Posts: 68993
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3/18/2022  11:59 AM
NYKBocker wrote:
martin wrote:
NYKBocker wrote:
smackeddog wrote:
martin wrote:
smackeddog wrote:Weirdly my sister's child got covid and she didn't (despite sleeping in the same room), and a few weeks later her partner has got covid and hasn't passed it on to her. How common is this? Have people encountered this? (either people they live with not passing it on or vice versa)? I've known a few people. Is it luck? Are some people more resistant to it? Is there much info about some people having an immunity to it?

I've known may families like this

I do wonder if it’s a fluke, or what the rates are of people with a robust natural immunity/resistance to the spiked protein, I’ve only read one or two articles and very small studies mentioning the research into it and even those weren’t really sure what’s going on.

At the beginning of the pandemic my wife got COVID. I was sleeping in the same bed for 2 nights. Until she finally got tested and tested positive. I took care of her giving her food and what not. I never got it. My family then went ahead and got the vaccine and boostered. Got a grandson and he is now 7 months olds. We babysit and I am with him almost everyday. My daughter and son-in-law got COVID at the beginning of the year and my grandson got it as well. They were both vaccinated. I still took care of my grandson. I just said...well I am getting it now. I am holding him and kissing him and everything. I never got COVID. So....

In my family, my wife, 2 daughters, son-in-law and grandson got COVID. Myself, 2 sons and daughter-in-law never got COVID. It is weird.

EDIT: I have been tested multiple times. I play basketball unmasked. I go to the gym unmasked after the NY mask mandate was lifted.

Obviously you are super human and we should all be drinking your blood

One word of advice for you.... commando

Some life lessons right there

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smackeddog
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3/18/2022  5:00 PM    LAST EDITED: 3/18/2022  5:10 PM
NYKBocker wrote:
martin wrote:
NYKBocker wrote:
smackeddog wrote:
martin wrote:
smackeddog wrote:Weirdly my sister's child got covid and she didn't (despite sleeping in the same room), and a few weeks later her partner has got covid and hasn't passed it on to her. How common is this? Have people encountered this? (either people they live with not passing it on or vice versa)? I've known a few people. Is it luck? Are some people more resistant to it? Is there much info about some people having an immunity to it?

I've known may families like this

I do wonder if it’s a fluke, or what the rates are of people with a robust natural immunity/resistance to the spiked protein, I’ve only read one or two articles and very small studies mentioning the research into it and even those weren’t really sure what’s going on.

At the beginning of the pandemic my wife got COVID. I was sleeping in the same bed for 2 nights. Until she finally got tested and tested positive. I took care of her giving her food and what not. I never got it. My family then went ahead and got the vaccine and boostered. Got a grandson and he is now 7 months olds. We babysit and I am with him almost everyday. My daughter and son-in-law got COVID at the beginning of the year and my grandson got it as well. They were both vaccinated. I still took care of my grandson. I just said...well I am getting it now. I am holding him and kissing him and everything. I never got COVID. So....

In my family, my wife, 2 daughters, son-in-law and grandson got COVID. Myself, 2 sons and daughter-in-law never got COVID. It is weird.

EDIT: I have been tested multiple times. I play basketball unmasked. I go to the gym unmasked after the NY mask mandate was lifted.

Obviously you are super human and we should all be drinking your blood

One word of advice for you.... commando

😂

Here are a couple of articles, on people who haven’t got covid (not he benefits of going commando unfortunately)

https://www.theguardian.com/world/2022/mar/02/scientists-seek-to-solve-mystery-of-why-some-people-do-not-catch-covid

Phoebe Garrett has attended university lectures without catching Covid; she even hosted a party where everyone subsequently tested positive except her. “I think I’ve knowingly been exposed about four times,” the 22-year-old from High Wycombe said.

In March 2021, she participated in the world’s first Covid-19 challenge trial, which involved dripping live virus into her nose and pegging her nostrils shut for several hours, in a deliberate effort to infect her. Still her body resisted.

“We had multiple rounds of tests, and different methods of testing: throat swabs, nose swabs, other types of swabs that I’d never done before like nasal wicks – where you hold a swab in your nose for a minute – as well as blood tests, but I never developed symptoms, never tested positive,” Garrett said. “My mum has always said that our family never gets flu, and I’ve wondered if there’s maybe something behind that.”

Most people know someone who has stubbornly resisted catching Covid, despite everyone around them falling sick. Precisely how they do this remains a mystery, but scientists are beginning to find some clues.

The hope is that identifying these mechanisms could lead to the development of drugs that not only protect people from catching Covid, but also prevent them from passing it on.

Garrett is not the only challenge trial participant to have avoided becoming infected. Of the 34 who were exposed to the virus, 16 failed to develop an infection (defined as two consecutive positive PCR tests) – although around half of them transiently tested positive for low levels of the virus, often several days after exposure….

Possibly, this was a reflection of the immune system rapidly shutting down an embryonic infection. “In our previous studies with other viruses, we have seen early immune responses in the nose that are associated with resisting infection,” said Prof Christopher Chiu at Imperial College London, who led the study. “Together, these findings imply that there is a struggle between the virus and host, which in our ‘uninfected’ participants results in prevention of infection taking off.”

Some of them also reported some mild symptoms, such as a stuffy nose, sore throat, tiredness, or headache – although, since these commonly occur in everyday life, they may have been unrelated to virus exposure.

“Either way, levels of the virus didn’t climb high enough to trigger detectable levels of antibodies, T cells or inflammatory factors in the blood that are usually associated with symptoms,” Chiu said.

Other studies also suggest it is possible to shake off Covid during the earliest stages of infection, before it establishes a proper foothold. For instance, during the first wave of the pandemic, Dr Leo Swadling at University College London and colleagues intensively monitored a group of healthcare workers who were regularly exposed to infected patients, but who never tested positive or developed antibodies themselves. Blood tests revealed that around 15% of them had T cells reactive against Sars-CoV-2, plus other markers of viral infection.

…….They have since discovered antibodies to this peptide in up to 68% of blood donors from Stockholm. The research, which has not yet been peer-reviewed, could suggest that immune responses triggered by H1N1 influenza – which was responsible for the 2009-10 swine flu pandemic – and possibly related subsequent strains, may equip people with partial, though not complete, protection against Covid-19. “It provides a cushion, but it won’t protect you if an infected person coughs in your face,” Söderberg-Nauclér said.

A small proportion of people may even be genetically resistant to Covid-19. In October, an international consortium of researchers launched a global hunt to find some of them, in the hope of identifying protective genes.

“We are not looking for common gene variants that provide modest protection against infection, what we are looking for is potentially very rare gene variants that completely protect someone against infection,” said Prof András Spaan at the Rockefeller University in New York, who is leading the research

They are particularly interested in people who shared a home and bed with an infected person, and avoided infection themselves. “For instance, the other day I was talking to an elderly lady from the Netherlands, who took care of her husband during the first wave. The husband was eventually admitted to the ICU, but she spent the week before taking care of him, sharing the same room, and without access to face masks,” said Spaan. “We cannot explain why she did not get infected.”

Such resistance is known to exist for other diseases, including HIV, malaria, and norovirus. In these cases, a genetic defect means some people lack a receptor used by the pathogen to enter cells, so they cannot be infected. “It could well be that, in some individuals, there is such a defect in a receptor used by Sars-CoV-2,” Spaan said.


https://www.theguardian.com/commentisfree/2022/mar/07/never-caught-covid-immune-systems-vaccines

martin
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3/30/2022  6:06 PM
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martin
Posts: 68993
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3/30/2022  6:06 PM
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Allanfan20
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3/30/2022  8:01 PM
martin wrote:

Damn. How much longer until we have to take these boosters. I am pro-vaccine but when will enough be enough?

“Whenever I’m about to do something, I think ‘Would an idiot do that?’ and if they would, I do NOT do that thing.”- Dwight Schrute
ToddTT
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3/30/2022  8:10 PM
Allanfan20 wrote:
martin wrote:

Damn. How much longer until we have to take these boosters. I am pro-vaccine but when will enough be enough?

My job wants us back in the office, so I should probably get yet another booster.

Oh wait. Maybe I should tell my job to go **** themselves!!! Yeah, I like that plan better!

smackeddog
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3/31/2022  1:11 PM
Allanfan20 wrote:
martin wrote:

Damn. How much longer until we have to take these boosters. I am pro-vaccine but when will enough be enough?

It's a good question- everything has ben quiet on the vaccination front for months- would love an update on the different vaccines in development, will the boosters switch to targeting the omicron strain, or is it safer to focus on the more severe earlier strains? Any new knowledge on how exactly the virus works and the impact it has on people. Just feels like all advancement in knowledge stopped early last year

Clean
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4/2/2022  11:14 AM
Just posting my usual be careful guys. I know 3 people in totally different places who got it in about a 3 day window. Now with every government operating like its no longer a thing it will start to spread again once peoples immunities wane.
Clean
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4/11/2022  3:28 PM
Clean
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7/22/2022  9:36 AM
We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.
GustavBahler
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7/22/2022  9:45 AM
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

Got my sense of smell back after my first bout of long covid. Never had coughs that made me gasp for air. Still do from time to time.

With long covid I would have 5 cups of strong coffee in under 2 hours, followed it up with an extra strength 5 hour energy. No buzz, no "jolt" like the old cola. Passed out a half an hour later, slept for 4-5 hours. After more than 8 hours of sleep the night before. Dont take the prospect of long covid lightly. Still got tired after the vaccines, but I didnt have some of the other symptoms, the second time around.

BigDaddyG
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7/22/2022  11:19 AM
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

Yeah, I got infected from a relative who is a medical professional last month. Symptoms were mild. Saw throat, slight respiratory infection with sudden onsets of fatigue that would pop up throughout the day. First time I ever tested positive. I'm in an area where reported cases are higher than they were the past two years, but the severity is less. And that's reported cases. They estimate the actual infection rate may be 6X higher.
Always... always remember: Less is less. More is more. More is better and twice as much is good too. Not enough is bad, and too much is never enough except when it's just about right. - The Tick
Clean
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7/22/2022  7:59 PM
KnickDanger
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7/22/2022  9:15 PM    LAST EDITED: 7/22/2022  9:16 PM
GustavBahler wrote:
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

Got my sense of smell back after my first bout of long covid. Never had coughs that made me gasp for air. Still do from time to time.

With long covid I would have 5 cups of strong coffee in under 2 hours, followed it up with an extra strength 5 hour energy. No buzz, no "jolt" like the old cola. Passed out a half an hour later, slept for 4-5 hours. After more than 8 hours of sleep the night before. Dont take the prospect of long covid lightly. Still got tired after the vaccines, but I didnt have some of the other symptoms, the second time around.

Your experience sounds somewhat similar to mine. I had Covid at the very beginning of the Pandemic -- was like a bad flu. But Long Haul has included distorted sense of smell (still not "normal"), intermittent infections in eyes and ears, and the fatigue thing with lots of naps. Vaxed twice and boosted then got the Omicron in January. Honestly the second vax and boost made me sicker. I feel better these days but fcould be just a new normal. Of course officially becoming a senior citizen may factor in as well!

smackeddog
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7/23/2022  4:57 AM
BigDaddyG wrote:
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

Yeah, I got infected from a relative who is a medical professional last month. Symptoms were mild. Saw throat, slight respiratory infection with sudden onsets of fatigue that would pop up throughout the day. First time I ever tested positive. I'm in an area where reported cases are higher than they were the past two years, but the severity is less. And that's reported cases. They estimate the actual infection rate may be 6X higher.

Me and my sister still haven't had it yet, but seems like every last covid holdout is getting it this time round- it's coming for us! What's the holdout rate like on these boards? Have most posters had it by now?

Clean
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7/23/2022  9:53 AM
Never had it yet. I have not gone outside without a mask since this started. Now I also live alone so no chance I can get it from someone else in the house either.
Clean
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7/30/2022  5:06 PM
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

It looks like this was true. This new variant evade immunity.

This is three days apart!

martin
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7/30/2022  6:29 PM
Clean wrote:
Clean wrote:We might have to dust this thread off again because it's getting really bad again with this BA.5 variant. I am hearing the numbers are the worst ever in some places. New variant and no mask mandates are a terrible mix. This one seems to avoid immunity more than previous variants. Once again I know multiple people who got it relatively recently and even after they recover have nasty covid cough fits. A few of them even never tested positive for covid but every symptom matches including dead giveaways like losing taste and smell.


If this is real that is crazy.

It looks like this was true. This new variant evade immunity.

This is three days apart!

It’s something else, just a not unexpected relapse from the medication of Paxlovid. I’ll find link

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