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GustavBahler wrote:Looks like I got "Covid arm" big red welt around the injection point. No biggie. They said its a problem if it happens in the first 4 hours. Took a couple of weeks, and no other side effects. Does make me wonder what the second shot will be like. We'll see...

Good luck with your 2nd shot.

martin wrote:

GustavBahler wrote:Looks like I got "Covid arm" big red welt around the injection point. No biggie. They said its a problem if it happens in the first 4 hours. Took a couple of weeks, and no other side effects. Does make me wonder what the second shot will be like. We'll see...

Can't tell if you mean by "Took a couple of week" as... for red welt to go away?

I have heard that massaging the injection point, especially if you get the big red welt or similar, helps. Could be just be some congestion of the vaccine itself.

Thanks for the tip. Was saying I didnt get covid arm until a couple of weeks later. Was half expecting it. Have worse reactions to tetanus shots. Arm swells up like a balloon. Will get the second dose in the other arm.

GustavBahler wrote:

martin wrote:

GustavBahler wrote:Looks like I got "Covid arm" big red welt around the injection point. No biggie. They said its a problem if it happens in the first 4 hours. Took a couple of weeks, and no other side effects. Does make me wonder what the second shot will be like. We'll see...

Can't tell if you mean by "Took a couple of week" as... for red welt to go away?

I have heard that massaging the injection point, especially if you get the big red welt or similar, helps. Could be just be some congestion of the vaccine itself.

The redness went away pretty fast. Thought it would last longer.

Welpee wrote:

GustavBahler wrote:

martin wrote:

GustavBahler wrote:Looks like I got "Covid arm" big red welt around the injection point. No biggie. They said its a problem if it happens in the first 4 hours. Took a couple of weeks, and no other side effects. Does make me wonder what the second shot will be like. We'll see...

Can't tell if you mean by "Took a couple of week" as... for red welt to go away?

I have heard that massaging the injection point, especially if you get the big red welt or similar, helps. Could be just be some congestion of the vaccine itself.

The redness went away pretty fast. Thought it would last longer.

Now what scares me is that Warrior player who got Covid after getting vaccinated. I know it's rare and nothing in life is 100% guaranteed, but it's an eye opener not to get too casual just because you got the shot.

Its the variants from the other side of the workd that concerns me Wether or not the booster shots can keep up. This virus is mutating very rapidly.

Its apocalyptic, and quite tragic, what's happening in India. They also have to deal with limited resources. Id like to see the US send equipment, and the manpower, if necessary to send not only vaccines, but to mass produce and distribute oxygen tanks.

smackeddog wrote:

GustavBahler wrote:

Bill Gates says no to sharing vaccine formulas with global poor to end pandemic Health advocates blast Microsoft billionaire for saying patent protections on life-saving vaccines must remain

https://www.salon.com/2021/04/26/bill-gates-says-no-to-sharing-vaccine-formulas-with-global-poor-to-end-pandemic_partner/

Dont believe these billionaires understand how sick a large part of the world is of them. They should care before it reaches a tipping point.

Disgusting- colonial mentality by Bill Gates and co

Feel like there are a ton of nuances to both what Bill Gates understands and what the reality is around the world.

Another take and I still feel this article glosses over a lot of big points but it's another perspective. I don't typically rely on WSJ for all sorts of reasons but Dr. Scott Gottlieb (board member Pfizer so take that with a huge grain of salt) is pretty well known in the COVID sphere.

https://www.wsj.com/articles/patent-busting-wont-help-vaccinate-the-world-faster-11620591133?mod=e2two

Patent Busting Won’t Help Vaccinate the World Faster
The solution is to ease restrictions on exporting shots and build more production capacity.

While the U.S. Covid pandemic has been contained, the situation in many countries, particularly India, is dire. It’s essential to get as much of the world vaccinated as quickly as possible to save lives and prevent new variants from emerging. The Biden administration’s support for breaking vaccine patents is a bad precedent that would do no immediate good and substantial long-term harm.

There isn’t enough vaccine supply to meet world-wide demand. Many countries have access only to inferior vaccines produced in Russia or China. Understandably, they want the same safe and effective vaccines that are available to Americans. By the end of 2022, U.S. manufacturers will produce more than 12 billion doses of high-quality vaccines, enough to satisfy global needs. And other vaccine candidates are in the pipeline and may be authorized over the next year. But over the next six months, global supply will remain tight.

The Biden administration caved to pressure at the World Trade Organization to support waiving intellectual-property protections for Covid vaccines. Some activists have declared victory, even though patent breaking wouldn’t solve the immediate problem and could make a global agreement much more difficult. France, Germany and the U.K. all oppose the idea, and the WTO should reject it. Here are four productive steps the developed world could take instead:

First, the U.S. government should stop hoarding doses and make them available for export. Some of the biggest vaccine makers have shown that their manufacturing is stable and growing. The supply chain is reliable, and the U.S. doesn’t need to stockpile hundreds of millions of doses. More can be made available on a rolling basis to countries like India and Brazil.

Second, countries that produce quality vaccines such as Belgium, France, Japan, Australia and the U.K., to name only a few, should invest in a major expansion of manufacturing facilities and the attendant supply chain, in return for a guarantee that a high percentage of the vaccines that flow from these efforts go to low- and middle-income nations. This would secure stable production and guarantee a steady supply of high-quality vaccines for vulnerable nations.

Third, the U.S. should work with the World Health Organization to deal with legitimate liability concerns from U.S. manufacturers that donate vaccines to low-income nations. Companies are worried about being sued by all manner of individuals all over the world. Patients need recourse if they’re harmed, and vaccine companies need some backstop on unbounded liabilities. This could take the form of a compensation system for injuries, overseen by the World Bank. Similar measures are in place for manufacturers that make doses available to Americans under an emergency-use authorization.

Finally, American drug makers can work with existing vaccine manufacturers in middle-income nations such as Brazil and South Africa. Some of these countries may be able to expand their capacity to take on international “fill and finish” capacity, receiving vaccines in bulk and placing them in smaller vials for distribution, the insufficiency of which could otherwise become a bottleneck. These kinds of tech transfers could take time—at least six months and probably a year or longer—and would need to be started in short order.

All these steps depend on a global agreement to protect intellectual property. The proposal to suspend portions of the WTO’s agreement on intellectual property has long been sought by China as a way to pirate Western intellectual property legally. Drug makers can work exclusively with leaders in the European Union to put together a package that would address immediate and long-term needs of lower-income nations while continuing to protect intellectual property, which is vital to the development of future vaccines and therapies.

Many nations are still suffering deeply from Covid-19. There’s no time to waste on symbolic measures that set a poor precedent and don’t solve the crisis.

Dr. Borio is a senior fellow for global health at the Council on Foreign Relations and was Director for Medical and Biodefense Preparedness at the National Security Council, 2017-19. Dr. Gottlieb is a resident fellow at the American Enterprise Institute and a board member of Pfizer. He was commissioner of the Food and Drug Administration, 2017-19.

EARLY RESEARCH FINDS EXTRACTS FROM SWEET WORMWOOD PLANT CAN INHIBIT THE COVID-19 VIRUS

Early Research Finds Extracts from Sweet Wormwood Plant Can Inhibit the COVID-19 Virus
Laboratory Findings Suggest Artemisia Annua May Point to Treatment for SARS-CoV-2

May 4, 2021
A team of researchers that includes Worcester Polytechnic Institute Biology Professor Pamela Weathers has found that extracts from the leaves of the Artemisia annua plant, a medicinal herb also known as sweet wormwood, inhibit the replication of the SARS-CoV-2 virus and two of its recent variants.

The team, which included researchers from Columbia University in New York and the University of Washington at Seattle, also found that extracts of the plant were more effective against the virus when levels of a key therapeutic compound in the plant, artemisinin, were low. The in vitro findings led the researchers to suggest that one or more compounds in Artemisia annua, or A. annua, that have not yet been identified may point to a safe, low-cost therapeutic treatment for SARS-CoV-2, the virus responsible for the COVID-19 pandemic.

The work was described in an article published in the Journal of Ethnopharmacology.

“Artemisia annua has been studied extensively, and it has been used safely for more than 2,000 years in traditional medicine to treat a variety of fever-related ailments,” Weathers said. “A. annua could provide clues to new safe, cost-effective small molecule therapies or even be used as an antiviral nutraceutical.”

The researchers soaked dried leaves of A. annua, obtained from four continents in hot water and tested the solutions against SARS-CoV-2 and two variants originating from the United Kingdom and South Africa. Some leaf samples were 12 years old but still potent against the virus. Researchers also tested artemisinin alone against the viruses, but the plant extracts were more potent. Artemisinin is a compound naturally produced by the plant, but is usually extracted, chemically modified, and developed in combination with other drugs to treat malaria.

Results showed that the extracts of A. annua did not block the virus from entering cells but interfered with the virus’ ability to replicate, thus killing it. In addition, the anti-replication activity did not appear linked to artemisinin or flavonoids, which are natural substances in the plants.

Weathers has long studied different strains of Artemisia, which are grown around the world. She recently was a co-author on papers exploring the anti-malaria properties of artemisinin and the impact of A. annua and artemisinin extracts on the malaria parasite. She also is collaborating on a study at WPI to identify compounds in A. annua that may be effective against the bacteria responsible for tuberculosis.

Weathers said more work is needed to identify the compound or combination of compounds in A. annua responsible for inhibiting viral replication.

“These findings add to evidence emerging from other labs around the world that this plant possesses compounds that could help patients who are infected with COVID-19,” Weathers said. “We also know that the plant possesses compounds that inhibit inflammation and the formation of scar-like tissues known as fibrosis, which also affect patients with COVID-19. Together, these characteristics point to a plant that bears a lot more study.”

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